Despite phenomenal advances in injectables, transdermals, inhalable, nasal and other routes of administration oral route of administration remains well ahead as the most preferred delivery route, with tablets emerging as the most popular solid oral dosage form used today. However various factors like difficulty in swallowing, unavailability of water etc lead to high incidence of patient non compliance which in turn can lead to ineffective therapy and increased health care cost. Methods to improve patient’s compliance have always attracted scientists towards the development of fancy oral drug delivery systems. Among them, mouth dissolving drug delivery systems (MDDDS) have acquired an important position in the market by overcoming previously encountered administration problems and contributing to extension of patent life. Mouth dissolving tablet are solid unit dosage forms, which dissolve rapidly in mouth without chewing and water. Within the patient population Mouth dissolving tablets has applications in some increasingly important demographic groups such as pediatric and geriatric patient who have either difficulty or disliking for swallowing conventional tablet and capsules. In this article various aspects of mouth dissolving tablets are covered including: formulation aspects, evaluation techniques, technologies available and the advances made so far in the field of fabrication of mouth dissolving tablets.
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